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Skimmin

Cat. No. M16335

All AbMole products are for research use only, cannot be used for human consumption.

Skimmin Structure
Synonym:

Umbelliferone glucoside

Size Price Availability Quantity
5mg USD 65 In stock
10mg USD 105 In stock
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Quality Control & Documentation
Biological Activity

Skimmin (Umbelliferone glucoside) is a major pharmacologically active and orally active molecule present in Hydrangea paniculata, a medical herb used in traditional Chinese medicine as an anti-inflammatory agent. Skimmin has renal protective activity. Skimmin reduces cardiac fibrosis as well as decreasing TNF-α, IL-6, IL1β, and TGFβ1 in cardiac tissues.

Chemical Information
Molecular Weight 324.28
Formula C15H16O8
CAS Number 93-39-0
Solubility (25°C) DMSO 80 mg/mL
Storage 4°C, protect from light
References

[1] Rui-Kai Liang, et al. Kaohsiung J Med Sci. Skimmin protects diabetic cardiomyopathy in streptozotocin-induced diabetic rats

[2] Guoqiang Zhang, et al. Front Pharmacol. Skimmin Improves Insulin Resistance via Regulating the Metabolism of Glucose: In Vitro and In Vivo Models

[3] Yan Lou, et al. J Pharm Biomed Anal. Determination and pharmacokinetic study of skimmin by UHPLC-MS/MS in rat plasma

[4] Sen Zhang, et al. Evid Based Complement Alternat Med. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition

[5] Sen Zhang, et al. Eur J Pharmacol. Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats

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Keywords: Skimmin, Umbelliferone glucoside supplier, IL Receptor/Related, inhibitors, activators

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