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SJF-1528 is a potent EGFR PROTAC degrader with DC50 values of 39.2 nM and 736.2 nM for wild-type EGFR in OVCAR8 cells and Exon 20 Ins mutated EGFR in HeLa cells.
| Molecular Weight | 1030.6 |
| Formula | C55H57ClFN7O8S |
| CAS Number | 2230821-38-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light, sealed |
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