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SJ 172550 is a mDMX inhibitor. Reversibly binds MDMX (EC50 = 2.3 μM). Inhibits the MDMX-p53 interaction in cultured retinoblastoma cells; frees p53 to induce apoptosis.
| Molecular Weight | 428.87 |
| Formula | C22H21ClN2O5 |
| CAS Number | 431979-47-4 |
| Solubility (25°C) | DMSO 42.89 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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