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Sivopixant

Cat. No. M21200

All AbMole products are for research use only, cannot be used for human consumption.

Sivopixant Structure
Synonym:

S-600918

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Quality Control & Documentation
Biological Activity

The P2X3 ligand-gated ion channel antagonist sivopixant (S-600918) is an oral phase II candidate compound for the study of refractory chronic cough.

Chemical Information
Molecular Weight 507.93
Formula C25H22ClN5O5
CAS Number 2414285-40-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lorcan McGarvey, et al. Lung. A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 2b Trial of P2X3 Receptor Antagonist Sivopixant for Refractory or Unexplained Chronic Cough

[2] Douglas S Burgoyne. Am J Manag Care. Managed care considerations for the treatment of chronic cough

[3] Akio Niimi, et al. Eur Respir J. Randomised trial of the P2X3 receptor antagonist sivopixant for refractory chronic cough

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Keywords: Sivopixant, S-600918 supplier, P2 Receptor, inhibitors, activators

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