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SIS17 is a histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. SIS17 inhibits the demyristoylation HDAC11 substrate and serine hydroxymethyl transferase 2.
This compound is unstable in solutions, freshly prepared is recommended.
| Molecular Weight | 366.6 |
| Formula | C21H38N2OS |
| CAS Number | 2374313-54-7 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Son SI, et al. ACS Chem Biol. Activity-Guided Design of HDAC11-Specific Inhibitors.
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