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SIRT-IN-3

Cat. No. M13736

All AbMole products are for research use only, cannot be used for human consumption.

SIRT-IN-3 Structure

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Quality Control & Documentation
Biological Activity

SIRT-IN-3 is a potent SIRT inhibitor, with an IC50 of 17 μM for SIRT1. SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 μM and 235 μM for SIRT2 and SIRT3, respectively).

Chemical Information
Molecular Weight 212.25
CAS Number 1211-19-4
Solubility (25°C) DMSO 150 mg/mL
Storage 2-8°C, protect from light
References

[1] Jinli Wang, et al. Aging (Albany NY). NAD+ improved experimental autoimmune encephalomyelitis by regulating SIRT1 to inhibit PI3K/Akt/mTOR signaling pathway

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  Catalog
Abmole Inhibitor Catalog




Keywords: SIRT-IN-3 supplier, Sirtuin, inhibitors, activators

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