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Sirpiglenastat

Cat. No. M21577

All AbMole products are for research use only, cannot be used for human consumption.

Sirpiglenastat Structure
Synonym:

DRP-104

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Quality Control & Documentation
Biological Activity

Sirpiglenastat (DRP-104) is a broad acting glutamine (glutamine) antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing an effective antitumor immune response.

Chemical Information
Molecular Weight 441.48
Formula C22H27N5O5
CAS Number 2079939-05-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ryan S Alden, et al. Front Oncol. Glutamine metabolism and radiosensitivity: Beyond the Warburg effect

[2] Yumi Yokoyama, et al. Mol Cancer Ther. Sirpiglenastat (DRP-104) Induces Antitumor Efficacy through Direct, Broad Antagonism of Glutamine Metabolism and Stimulation of the Innate and Adaptive Immune Systems

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Keywords: Sirpiglenastat, DRP-104 supplier, inhibitors, activators

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