Free shipping on all orders over $ 500

Sinefungin

Cat. No. M8196

All AbMole products are for research use only, cannot be used for human consumption.

Sinefungin Structure
Synonym:

Adenosyl-Ornithine; A-9145

Size Price Availability Quantity
1mg USD 300 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Sinefungin blocks the methylation of bases in DNA and RNA, such as 5-methylcytosine or N6-methyladenosine, suggesting a role in gene expression. In addition, sinefugin is involved in physiological processes such as aging and carcinogenesis.

Chemical Information
Molecular Weight 381.39
Formula C15H23N7O5
CAS Number 58944-73-3
Solubility (25°C) Water ≥ 40 mg/mL
Storage -20°C, protect from light, dry, sealed
References

[1] Alessandra Galati, et al. The S-adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening

[2] Ludovic Decultot, et al. Asymmetric Total Synthesis of C9'- epi-Sinefungin

[3] Mukesh Kumar Yadav, et al. Sinefungin, a natural nucleoside analogue of S-adenosylmethionine, inhibits Streptococcus pneumoniae biofilm growth

[4] Sendilcoumare Kalimouttou, et al. Sinefungin-PLGA nanoparticles: drug loading, characterization, in vitro drug release and in vivo studies

[5] Xueqiang Yin, et al. Carbocyclic Sinefungin

Related Histone Methyltransferase Products
VTP50469

VTP50469 is a potent, highly selective and orally active inhibitor of Menin-MLL Interaction with a Ki value of 104 pM. VTP50469 has anti-leukemia activity.

BIX 01294 Trihydrochloride

BIX 01294 Trihydrochloride is a potent inhitor of G9a histone methyltransferase with IC50 of 2.7 μM.

EBI-2511

EBI-2511 is an orally active, potent inhibitor of EZH2 in Pfeffiera cells IC50 The value is 6 nM.

EPZ-5676

EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase.

EPZ004777

EPZ004777 is a potent, selective, small-molecule inhibitor of DOT1L with IC50 of 0.4 nM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Sinefungin, Adenosyl-Ornithine; A-9145 supplier, Histone Methyltransferase, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.