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Silydianin

Cat. No. M4596

All AbMole products are for research use only, cannot be used for human consumption.

Silydianin Structure
Size Price Availability Quantity
1mg USD 50 In stock
5mg USD 120 In stock
10mg USD 190 In stock
20mg USD 280 In stock
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Quality Control & Documentation
Biological Activity

Silydianin, the active ingredient of silythistle, has anti-collagenase and anti-elastic enzyme activities. Silydianin is a natural protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 17.38 μM. Silydianin inhibited the production and release of oxidation products in vitro.

Chemical Information
Molecular Weight 482.44
Formula C25H22O10
CAS Number 29782-68-1
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Alena Rajnochov Svobodov, et al. A pilot study of the UVA-photoprotective potential of dehydrosilybin, isosilybin, silychristin, and silydianin on human dermal fibroblasts

[2] Vahid Soleimani, et al. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review

[3] No authors listed. Milk Thistle

[4] Ludovico Abenavoli, et al. Milk thistle in liver diseases: past, present, future

[5] Małgorzata Zielińska-Przyjemska, et al. An in vitro study of the protective effect of the flavonoid silydianin against reactive oxygen species

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Abmole Inhibitor Catalog




Keywords: Silydianin supplier, Phosphatase, inhibitors, activators

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