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Sieboldin

Cat. No. M40439

All AbMole products are for research use only, cannot be used for human consumption.

Sieboldin Structure
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5mg USD 840 In stock
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Biological Activity

Sieboldin is a dihydrochalcone, which inhibits the production of advanced glycation end products (AGE) produced by bovine serum albumins (BSA), has free radical scavenging activity and cytotoxicity in cancer cell lines, and is also used to capture of methylglyoxal (MGO) from Malus baccata.

Chemical Information
Molecular Weight 452.41
Formula C21H24O11
CAS Number 18777-73-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Simón Miranda et al. Front Plant Sci. De novo transcriptome assembly and functional analysis reveal a dihydrochalcone 3-hydroxylase(DHC3H) of wild Malus species that produces sieboldin in vivo

[2] Zhengcao Xiao et al. Food Chem. Extraction, identification, and antioxidant and anticancer tests of seven dihydrochalcones from Malus 'Red Splendor' fruit

[3] Matthieu Gaucher et al. Phytochemistry. Histolocalization and physico-chemical characterization of dihydrochalcones: Insight into the role of apple major flavonoids

[4] Thomas Dugé de Bernonville et al. Phytochemistry. Dihydrochalcones: Implication in resistance to oxidative stress and bioactivities against advanced glycation end-products and vasoconstriction

[5] M A Rojo et al. Arch Biochem Biophys. Isolation, cDNA cloning, biological properties, and carbohydrate binding specificity of sieboldin-b, a type II ribosome-inactivating protein from the bark of Japanese elderberry (Sambucus sieboldiana)

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