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SHP2-IN-6 hydrochloride 

Cat. No. M29321

All AbMole products are for research use only, cannot be used for human consumption.

SHP2-IN-6 hydrochloride  Structure
Synonym:

JAB-3068 hydrochloride 

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Quality Control & Documentation
Biological Activity

SHP2-IN-6 hydrochloride is a potent SHP2 inhibitor that interferes with the MAPK signaling pathway and inhibits the proliferation of SHP2-expressing tumor cells with an IC50 value of 25.8 nM.

Chemical Information
Molecular Weight 513
Formula C22H27ClF2N6O2S
CAS Number 2169223-49-6
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage -20°C, protect from light, dry, sealed
References

[1] Ha Jung Lee, et al. Cells. Nalfurafine Hydrochloride, a κ-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells

[2] No authors listed. Carteolol

[3] Yurui Xu, et al. Int J Biol Macromol. Nanoparticles based on chitosan hydrochloride/hyaluronic acid/PEG containing curcumin: In vitro evaluation and pharmacokinetics in rats

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  Catalog
Abmole Inhibitor Catalog




Keywords: SHP2-IN-6 hydrochloride , JAB-3068 hydrochloride  supplier, Phosphatase, inhibitors, activators

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