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SGC2085 hydrochloride 

Cat. No. M28928

All AbMole products are for research use only, cannot be used for human consumption.

SGC2085 hydrochloride  Structure

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Quality Control & Documentation
Biological Activity

SGC2085 hydrochloride is a potent and selective inhibitor of coactivator associated arginine methyltransferase 1 (CARM1) with an IC50 of 50 nM. SGC2085 hydrochloride also selectively inhibits PRMT6 with an IC50 value of 5.2 μM, but not other PRMT proteins.

Chemical Information
Molecular Weight 348.87
Formula C19H25ClN2O2
CAS Number 1821908-49-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Related PRMTs Products
C7280948

C7280948 is an inhibitor of histone arginine methyltransferase PRMT1 with IC50 values of 12.75 uM.

EPZ015666

EPZ015666 is a potent, selective and orally bioavailable PRMT5 inhibitor with Ki of 5 nM, >20,000-fold selectivity over other PMTs.

SGC707

SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively.

EPZ020411

EPZ020411 is a potent and selective inhibitor of PRMT6 with IC50 of 10 nM, has >10 fold selectivity for PRMT6 over PRMT1 and PRMT8.

XY1

XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhibitor of PRMT3 with IC50 of 31 nM), but XY1 is completely inactive.

  Catalog
Abmole Inhibitor Catalog




Keywords: SGC2085 hydrochloride  supplier, PRMTs, inhibitors, activators

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