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SF 11 is a nPY Y2 antagonist (IC50 = 199 nM). Displays no affinity for Y1 receptor at concentrations up to 35 μM. Causes significant lethality in mice. Brain penetrant.
| Molecular Weight | 446.6 |
| Formula | C27H30N2O2S |
| CAS Number | 443292-81-7 |
| Solubility (25°C) | DMSO 44.66 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Neuropeptide Receptor Products |
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| JNJ-31020028
JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22 rat); >100-fold selective versus human Y1/Y4/Y5 receptors. |
| BIBO 3304 trifluoroacetate
BIBO 3304 trifluoroacetate is a highly selective NPY Y 1 receptor antagonist. |
| CYM 9484
CYM 9484 is a potent NPY Y 2 receptor antagonist. |
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NTNCB hydrochloride is a potent and selective non-peptidic NPY Y 5 antagonist. |
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