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Sertaconazole

Cat. No. M30991

All AbMole products are for research use only, cannot be used for human consumption.

Sertaconazole Structure
Synonym:

FI7056 free base

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Quality Control & Documentation
Biological Activity

Sertaconazole (FI7056 free base) is a broad-spectrum topical antifungal agent, exhibits anti-inflammatory activity via activation of a p38-COX-2-PGE2 pathway. Sertaconazole is also a microtubule inhibitor, shows antiproliferative effect, induces apoptosis and autophagy, and can also inhibit the migration of cells.

Chemical Information
Molecular Weight 437.77
Formula C20H15Cl3N2OS
CAS Number 99592-32-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Jomon Sebastian, et al. Naunyn Schmiedebergs Arch Pharmacol. Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly

[2] Alfonso Javier Carrillo-Muñoz, et al. Expert Rev Anti Infect Ther. Sertaconazole: an antifungal agent for the topical treatment of superficial candidiasis

[3] Jamie D Croxtall, et al. Drugs. Sertaconazole: a review of its use in the management of superficial mycoses in dermatology and gynaecology

[4] Alfonso J Carrillo-Muñoz, et al. Expert Rev Anti Infect Ther. Sertaconazole: updated review of a topical antifungal agent

[5] J Torres, et al. Int J Gynaecol Obstet. Sertaconazole in the treatment of mycoses: from dermatology to gynecology

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Keywords: Sertaconazole, FI7056 free base supplier, Antifungal, inhibitors, activators

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