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Serlopitant

Cat. No. M9185

All AbMole products are for research use only, cannot be used for human consumption.

Serlopitant Structure
Synonym:

VPD-737; MK-0594

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Quality Control & Documentation
Biological Activity

Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist. Serlopitant (0.25 and 4 mg) significantly decreased the primary end point of daily micturitions but not the secondary end points compared with placebo. Serlopitant was generally well tolerated.

Chemical Information
Molecular Weight 555.53
Formula C29H28F7NO2
CAS Number 860642-69-9
Solubility (25°C) DMSO 10 mM
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Frenkl TL, et al. J Urol. A multicenter, double-blind, randomized, placebo controlled trial of a neurokinin-1 receptor antagonist for overactive bladder.

Related Neurokinin Receptor Products
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Monohydroxy Netupitant is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.

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Maropitant

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Eprazinone dihydrochloride

Eprazinone is a mucolytic.

Fosaprepitant dimeglumine salt

Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended

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Keywords: Serlopitant, VPD-737; MK-0594 supplier, Neurokinin Receptor, inhibitors, activators

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