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Sennidin-B

Cat. No. M4423

All AbMole products are for research use only, cannot be used for human consumption.

Sennidin-B Structure
Size Price Availability Quantity
10mg USD 660 In stock
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Quality Control & Documentation
Biological Activity

Sennidin B can be isolated from Cassia Angustifolia and is an isomer of Sennidin A with lower activity than Sennidin A. Sennidin A inhibited HCV NS3 helicase with an IC50 value of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4). Sennidin A stimulates glucose incorporation.

Chemical Information
Molecular Weight 538.46
Formula C30H18O10
CAS Number 517-44-2
Form Solid
Storage 4°C, protect from light, dry, sealed
References

[1] Ling Li, et al. Effects of Glycosylation on Biodistribution and Imaging Quality of Necrotic Myocardium of Iodine-131-Labeled Sennidins

[2] Cuihua Jiang, et al. Exploring diagnostic potentials of radioiodinated sennidin A in rat model of reperfused myocardial infarction

[3] Yun Ji, et al. Necrosis targeted combinational theragnostic approach using radioiodinated Sennidin A in rodent tumor models

[4] Daigo Abe, et al. Sennidin stimulates glucose incorporation in rat adipocytes

[5] T Akao, et al. Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins

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