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Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. IC50 value: Target: In addition, it is known that Secalciferol mediates calcium and phosphorus homeostasis. Also Secalciferol inhibits calcium channels in osteosarcoma cells via suppressing the effects of 1α, 25-dihydroxyvitamin D3 and testosterone. Alternate studies indicate that Secalciferol can decrease the abundance of p53 and Pi-induced cytochrome c translocation. Furthermore, Secalciferol can increase cell proliferation in resting zone (RC) chondrocytes and inhibits matrix enzymes by possibly inhibiting the degradation of the matrix.
*The compound is unstable in solutions, freshly prepared is recommended
| Molecular Weight | 416.64 |
| CAS Number | 55721-11-4 |
| Storage | -20°C, protect from light, sealed |
[1] Vlastimil Kulda. [Vitamin D metabolism]
[3] R G MATHERS. Calciferol in tuberculosis
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