All AbMole products are for research use only, cannot be used for human consumption.
Scriptaid is an inhibitor of HDAC. It shows a greater effect on acetylated H4 than H3.
| Cell Experiment | |
|---|---|
| Cell lines | Human breast cancer cells MDA-MB-231 |
| Preparation method | Plating the cells at a cell density of 5000 cells/well in 12 well plates and treating them with scriptaid for up to 3 days. Use a Coulter counter to count the number of cell every day. |
| Concentrations | ~10 μg/mL |
| Incubation time | 3 days |
| Animal Experiment | |
|---|---|
| Animal models | Human breast carcinoma xenografts MDA-MB-231 |
| Formulation | DMSO |
| Dosages | 3.5 mg/kg |
| Administration | intraperitoneally for five consecutive days with 2 days rest each week for a total of 4 weeks |
| Molecular Weight | 326.35 |
| Formula | C18H18N2O4 |
| CAS Number | 287383-59-9 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related HDAC Products |
|---|
| Belinostat
Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM. |
| CUDC-101
CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively. |
| Givinostat hydrochloride monohydrate
ITF2357 (Givinostat, Gavinostat) is a histone deacetylase inhibitor. The IC50 values for maize HDAC preparations HD2, HD-1B and HD-1A are 10, 7.5 and 16 nM respectively. |
| Niltubacin
Niltubacin, as an inactive derivative of Tubacin, is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6. |
| Tubacin
Tubacin (Tubulin Acetylation Inducer) is a highly potent and selective, reversible cell-permeable inhibitor of HDAC6 with IC50 of 0.004µM. |
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