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SC 22716

Cat. No. M8021

All AbMole products are for research use only, cannot be used for human consumption.

SC 22716 Structure

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Quality Control & Documentation
Biological Activity

Cell-permeable leukotriene A4 (LTA4) hydrolase inhibitor that suppresses LTB4 production. Implicated in the pathogenesis of a number of diseases including inflammatory bowel disease and psoriasis.

Chemical Information
Molecular Weight 267.37
Formula C18H21NO
CAS Number 262451-89-8
Solubility (25°C) DMSO: 22 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Burcu Calışkan, et al. Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors

[2] Thomas D Penning, et al. Synthesis of potent leukotriene A(4) hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid

[3] T D Penning. Inhibitors of leukotriene A4 (LTA4) hydrolase as potential anti-inflammatory agents

[4] T D Penning, et al. Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase

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Keywords: SC 22716 supplier, inhibitors, activators

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