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SBP-7455

Cat. No. M21036

All AbMole products are for research use only, cannot be used for human consumption.

SBP-7455 Structure

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Quality Control & Documentation
Biological Activity

SBP-7455 is a dual-Specific ULK1/2 autophagy inhibitor with IC50s of 13 nM and 476 nM for ULK1 and ULK2 in ADP-Glo assay, respectively.

Chemical Information
Molecular Weight 354.33
Formula C16H17F3N4O2
CAS Number 1884222-74-5
Solubility (25°C) DMSO 71 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Huiyu Ren, et al. J Med Chem. Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: SBP-7455 supplier, ULK, inhibitors, activators

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