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BMP signaling agonist sb4 (SB-4) is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM. BMP signaling agonist sb4 activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9.
| Molecular Weight | 320.20 |
| Formula | C14H10BrNOS |
| CAS Number | 100874-08-6 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Eleftherios Pelechas, et al. Expert Opin Biol Ther. Etanercept biosimilar SB-4
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