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Saxagliptin H2O is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
| Molecular Weight | 333.43 |
| Formula | C18H25N3O2.H2O |
| CAS Number | 945667-22-1 |
| Solubility (25°C) | 60 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Dipeptidyl Peptidase Products |
|---|
| Sitagliptin phosphate monohydrate
Sitagliptin phosphate (MK-0431) is a potent inhibitor of dipeptidyl peptidase-4 (DPP-4) with IC50 of 19 nM. |
| Trelagliptin
Trelagliptin (SYR-472) is a novel once-weekly oral DPP-4 inhibitor for type 2 diabetes. |
| Alogliptin
Alogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. |
| Linagliptin
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM. |
| Vildagliptin
Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity. |
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