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Satraplatin

Cat. No. M28129

All AbMole products are for research use only, cannot be used for human consumption.

Satraplatin Structure
Synonym:

BMS182751; BMY45594; JM216

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Quality Control & Documentation
Biological Activity

Satraplatin is an alkylating agent, with potent antitumor effect.

Chemical Information
Molecular Weight 500.28
Formula C10H22Cl2N2O4Pt
CAS Number 129580-63-8
Form Solid
Solubility (25°C) DMF 10 mg/mL (ultrasonic and adjust pH to 1 with HCl, DMSO can inactivate Satraplatin's activity)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Thilo Zander, et al. Anticancer Res. Satraplatin Demonstrates High Cytotoxic Activity Against Genetically Defined Lymphoid Malignancies

[2] Gury Doshi, et al. Expert Opin Drug Metab Toxicol. Clinical and pharmacokinetic evaluation of satraplatin

[3] Ashish Bhargava, et al. Expert Opin Investig Drugs. Satraplatin: leading the new generation of oral platinum agents

[4] Guru Sonpavde, et al. Future Oncol. Satraplatin for the therapy of castration-resistant prostate cancer

[5] Hak Choy. Expert Rev Anticancer Ther. Satraplatin: an orally available platinum analog for the treatment of cancer

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Keywords: Satraplatin, BMS182751; BMY45594; JM216 supplier, DNA Alkylator/Crosslinker, inhibitors, activators

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