Free shipping on all orders over $ 500

SAR629 

Cat. No. M27967

All AbMole products are for research use only, cannot be used for human consumption.

SAR629  Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation.

Chemical Information
Molecular Weight 383.39
Formula C20H19F2N5O
CAS Number 1221418-42-3
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Francesca Galvani, et al. J Chem Inf Model. Mechanistic Modeling of Monoglyceride Lipase Covalent Modification Elucidates the Role of Leaving Group Expulsion and Discriminates Inhibitors with High and Low Potency

[2] T Bertrand, et al. J Mol Biol. Structural basis for human monoglyceride lipase inhibition

Related MAGL Products
JZL184

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

JZL 195

JZL195 is an effective FAAH and MAGL inhibitor with IC50 of 2 nM and 4 nM, respectively.

JW 642

Jw642 is a highly effective selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 7.6 nM, 14 nM and 3.7 nM in mouse, rat and human meninges, respectively.

MJN110

MJN110 is an orally effective and selective inhibitor of monacylglycerol lipase (MAGL) with IC50 of 9.1 nM and 2.1 nM against hMAGL and 2-arachidonic triglyceride (2-AG), respectively. It has strong anti-hyperalgesia activity.

JJKK-048

JJKK-048 is a cell penetrant ultrapotent and highly selective inhibitor of monoacylglycerol lipase (MAGL) that exhibits a low cross-reactivity with other endocannabinoid targets.

  Catalog
Abmole Inhibitor Catalog




Keywords: SAR629  supplier, MAGL, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.