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Sandramycin

Cat. No. M27625

All AbMole products are for research use only, cannot be used for human consumption.

Sandramycin Structure

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Quality Control & Documentation
Biological Activity

Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity.

Chemical Information
Molecular Weight 1221.32
Formula C60H76N12O16
CAS Number 100940-65-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yuya Komatani, et al. Org Lett. Solid-Phase Total Synthesis of Sandramycin and Its Analogues

[2] Katsushi Katayama, et al. Org Lett. Total synthesis of sandramycin and its analogues via a multicomponent assemblage

[3] D L Boger, et al. Bioorg Med Chem. Synthesis of key sandramycin analogs: systematic examination of the intercalation chromophore

[4] J A Matson, et al. J Antibiot (Tokyo). Sandramycin, a novel antitumor antibiotic produced by a Nocardioides sp. II. Structure determination

[5] J A Matson, et al. J Antibiot (Tokyo). Sandramycin, a novel antitumor antibiotic produced by a Nocardioides sp. Production, isolation, characterization and biological properties

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