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Samelisant free base

Cat. No. M28323

All AbMole products are for research use only, cannot be used for human consumption.

Samelisant free base Structure
Synonym:

SUVN-G3031 free base

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Quality Control & Documentation
Biological Activity

Samelisant (SUVN-G3031) free base is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant free base has a similar binding affinity towards human (hH3R; Ki=8.7 nM) and rat (rH3R;Ki=9.8 nM) H3R indicating no inter-species differences. Samelisant free base can be used for the research of sleep-related disorders.

Chemical Information
Molecular Weight 373.49
Formula C21H31N3O3
CAS Number 1394808-82-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Panagiotis V Samelis, et al. Cureus. Primary Congenital Hallux Varus: A Step-Cut Surgical Approach

[2] Evangelos Anagnostou, et al. Neurocirugia (Astur : Engl Ed). Two-step treatment of a giant skull vault hemangioma: A rare case report and literature review

[3] Panagiotis V Samelis, et al. Cureus. Factors Affecting Outcomes of Slipped Capital Femoral Epiphysis

[4] K A Ekmektzoglou, et al. Acta Gastroenterol Belg. Gastroesophageal junction and gastroesophageal junction carcinoma : a short update

[5] Maria Parapouli, et al. Appl Environ Microbiol. Characterization of a wild, novel nisin a-producing Lactococcus strain with an L. lactis subsp. cremoris genotype and an L. lactis subsp. lactis phenotype, isolated from Greek raw milk

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Keywords: Samelisant free base, SUVN-G3031 free base supplier, Histamine Receptor, inhibitors, activators

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