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Salvinorin A is a potent, non-nitrogenous κ opioid selective receptor agonist. Salvinorin A is isolated from Salvia divinorum. Salvinorin A displays high affinity at both native (Ki=4.3 nm) and cloned (Ki=16 nm) κ -opioid receptors. Preliminary studies suggest that Salvanorin A is chemically unique among the psychtropic drugs and does not bind to any known receptor.
| Molecular Weight | 432.46 |
| Formula | C23H28O8 |
| CAS Number | 83729-01-5 |
| Solubility (25°C) | DMSO: ≥10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Patrick Zimdars, et al. A Protecting-Group-Free Synthesis of (-)-Salvinorin A
[3] Katarzyna Socała, et al. Salvinorin A Does Not Affect Seizure Threshold in Mice
[4] Jeremy J Roach, et al. A review of salvinorin analogs and their kappa-opioid receptor activity
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