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Salvianolic-acid-B

Cat. No. M4140

All AbMole products are for research use only, cannot be used for human consumption.

Salvianolic-acid-B Structure
Synonym:

Dan Shen Suan B; Lithospermic acid B

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mg USD 60 In stock
20mg USD 100 In stock
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Quality Control & Documentation
Biological Activity

Salvianolic acid B is a cell protective antioxidant and free radical scavenger being investigated for a variety of conditions from ischemic heart disorders to Alzheimer′s disease. Several mechanisms of action have been proposed including EGFR, PDGF and MMP-9 inhibition and inhibition of the TGF-β1/Smads and NF-κB signaling pathways. Salvianolic acid B acts as scavengers of reactive oxygen species, reduces the adherence of leukocytes to endothelial cells, inhibits matrix metalloproteinases and inflammation. It has cardioprotective effects as it reduces lipid peroxidation in damaged cardiac tissue and decreases the leakage of lactic acid dehydrogenase.

*The compound is unstable in solutions, freshly prepared is recommended.

Product Citations
Chemical Information
Molecular Weight 718.62
Formula C36H30O16
CAS Number 115939-25-8
Solubility (25°C) DMSO 20 mg/mL
Water 25 mg/mL (ultrasonic and adjust pH to 3 with HCl)
Storage Powder -20°C 3 years ; 4°C 2 years
References

[1] Jia-Ming Sun, et al. Salvianolic acid-B improves fat graft survival by promoting proliferation and adipogenesis

[2] Dong Wang, et al. Salvianolic acid B attenuates oxidative stress-induced injuries in enterocytes by activating Akt/GSK3β signaling and preserving mitochondrial function

[3] Shuxia Tian, et al. Salvianolic acid B blocks hepatic stellate cell activation via FGF19/FGFR4 signaling

[4] Chang-Ling Li, et al. Salvianolic acid B improves myocardial function in diabetic cardiomyopathy by suppressing IGFBP3

[5] Xiang Yin, et al. Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone

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Keywords: Salvianolic-acid-B, Dan Shen Suan B; Lithospermic acid B supplier, Autophagy, inhibitors, activators

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