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Salsolinol is the condensation product of acetaldehyde and dopamine. Salsolinol is a potential neurotoxin suspected to contribute to alcohol abuse. It appears that salsolinol excites the ventral tegmental area (VTA) dopamine neurons indirectly by activating μ-opioid receptors (MORs), which inhibit GABA neurons in the VTA.
| Molecular Weight | 260.13 |
| Formula | C10H13NO2 · HBr |
| CAS Number | 59709-57-8 |
| Solubility (25°C) | Water: 5 mg/mL warmed |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Magdalena Kurnik-Łucka, et al. Salsolinol-neurotoxic or Neuroprotective?
[4] Emmy Tuenter, et al. Mood Components in Cocoa and Chocolate: The Mood Pyramid
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