SAG 21k

Cat. No. M7243

All AbMole products are for research use only, cannot be used for human consumption.

Synonym:

Hedgehog agonist 1

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.

SAG 21k is a potent Hedgehog signaling activator (EC₅₀ = 0.4 nM). Orally bioavailable and brain penetrant.

Molecular Weight	556.07
Formula	C29H28ClF2N3O2S
CAS Number	946002-48-8
Solubility (25°C)	DMSO 40 mg/mL
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related Hedgehog Products
Cyclopamine Cyclopamine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling.
LY2940680 LY2940680 is a potent Hedgehog inhibitor with potential anticancer activity.
LDE225 LDE225 (NVP-LDE225; Sonidegib) is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
PF-5274857 PF-5274857 is a novel Smoothened antagonist, inhibits Hedgehog signaling with IC50 and Ki values of 5.8 nM and 4.6 nM, respectively.
Jervine Jervine is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog signaling.

Catalog