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SAfit2 is a potent inhibitor of FK506-binding protein 51 (FKBP51) with a Ki value of 6 nM. SAfit2 has been used as a potential agent in the study of major depression, obesity, and chronic pain.
| Molecular Weight | 802.99 |
| Formula | C46H62N2O10 |
| CAS Number | 1643125-33-0 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | Powder -20°C |
| Related FKBP (FK506-binding protein) Products |
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| Shield-1
Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD) |
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