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Sabatolimab

Cat. No. M25047

All AbMole products are for research use only, cannot be used for human consumption.

Sabatolimab Structure
Synonym:

MBG453

Size Price Availability Quantity
100ug USD 150 In stock
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Quality Control & Documentation
Biological Activity

Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells.

Chemical Information
CAS Number 2252262-24-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Sofía Huerga-Domínguez, et al. Cancers (Basel). Updates on the Management of Acute Myeloid Leukemia

[2] Stephanie Schwartz, et al. Immunother Adv. Characterization of sabatolimab, a novel immunotherapy with immuno-myeloid activity directed against TIM-3 receptor

[3] Yasmin Abaza, et al. Cells. Immune Checkpoint Inhibition in Acute Myeloid Leukemia and Myelodysplastic Syndromes

[4] Valeria Santini. Curr Opin Oncol. Advances in myelodysplastic syndrome

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Keywords: Sabatolimab, MBG453 supplier, inhibitors, activators

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