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S-(+)-Ketoprofen (Compound 1, Actron, (S)-Ketoprofen, Dexketoprofen) is a potent inhibitor of cyclooxygenase (COX) with IC50 of 1.9 nM and 27 nM for COX-1 and COX-2, respectively.
| Molecular Weight | 254.28 |
| Formula | C16H14O3 |
| CAS Number | 22161-81-5 |
| Solubility (25°C) | DMSO 51 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Tiffany Yvonne Loh, et al. Indian J Med Res. Ketoprofen-induced photoallergic dermatitis
[5] Eva Neirinckx, et al. Vet J. Chiral inversion of R(-) to S(+) ketoprofen in pigs
| Related COX Products |
|---|
| Firocoxib
Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2. |
| Celecoxib
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
| Nepafenac
Nepafenac is an analgesic selective inhibitor of COX-2. |
| Ampiroxicam
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
| Bromfenac Sodium
Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. |
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Products are for research use only. Not for human use. We do not sell to patients.
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