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Levamisole ((-)-Levamisole), an anthelmintic agent with immunomodulatory properties. Levamisole acts as a positive allosteric modulator (PAM) for the α3β2 (EC50=300 μM) and α3β4 (EC50=100 μM) subtype of nAChRs. Orally active.
| Molecular Weight | 204.29 |
| Formula | C11H12N2S |
| CAS Number | 14769-73-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Cristina López-Sánchez, et al. JAMA Dermatol. Levamisole-Induced Vasculopathy
[3] Noah Scheinfeld, et al. Am J Clin Dermatol. Levamisole in dermatology : a review
[4] W K Amery, et al. Int J Immunopharmacol. Levamisole, the story and the lessons
[5] No authors listed. Lancet. Levamisole--a cautionary note
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