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(S)-(-)-BAY K 8644

Cat. No. M5077

All AbMole products are for research use only, cannot be used for human consumption.

(S)-(-)-BAY K 8644 Structure
Synonym:

(S)-(-)-Bay-K-8644; (-)-BAY-R-5417; (-)-BAY-K-8644

Size Price Availability Quantity
10mM*1mL in DMSO USD 165 In stock
5mg USD 150 In stock
10mg USD 230 In stock
25mg USD 480 In stock
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Biological Activity

(S)-Bay K 8644 (100 nM) increased whole-cell Ca2+ currents in A7r5 smooth muscle cells but effectively blocked further stimulation by 1 microM FPL 64176.(-)-S-Bay K 8644 enhanced transcoronary exchange more markedly than (+/-)-Bay W 5035 or (+/-)-Bay T 5006, reflecting the differences in coronary constrictor activity.

Chemical Information
Molecular Weight 356.3
Formula C16H15F3N2O4
CAS Number 98625-26-4
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Rump AF,et.al. Gen Pharmacol. Influence of (-)-S-Bay K 8644, (+/-)-Bay W 5035 and (+/-)-Bay T 5006 on hemodynamics and FITC-dextran 3 elution kinetics in isolated rat hearts.

[2] Rampe D,et.al. Mol Pharmacol. Functional interactions between two Ca2+ channel activators, (S)-Bay K 8644 and FPL 64176, in smooth muscle.

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Keywords: (S)-(-)-BAY K 8644, (S)-(-)-Bay-K-8644; (-)-BAY-R-5417; (-)-BAY-K-8644 supplier, Calcium Channel, inhibitors, activators

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