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S-Adenosylhomocysteine, an intermediate in the synthesis of cysteine and adenosine, is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM.
Mol Nutr Food Res. 2023 Feb 3;e2101052.
Oxidative Stress Mediated by N6‐Methyladenosine Methylation Contributes to High‐Fat Diet Induced Male Reproductive Dysfunction
S-Adenosylhomocysteine purchased from AbMole
| Molecular Weight | 384.41 |
| Formula | C14H20N6O5S |
| CAS Number | 979-92-0 |
| Solubility (25°C) | DMSO ≥ 10 mg/mL |
| Storage | -20°C, protect from light, dry, sealed |
[3] Joy Xin Wang, et al. Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine
| Related METTL3 Products |
|---|
| STM2457
STM2457 is a first-in-class, potent and specific, orally active METTL3 inhibitor with an IC50 of 16.9 nM and excellent in vivo activity. |
| UZH2
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM. |
| STC-15
STC-15 is a METTL3 inhibitor used in the study of proliferative diseases such as cancer and autoimmune diseases. |
| STM2120
STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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