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S 32826

Cat. No. M7238

All AbMole products are for research use only, cannot be used for human consumption.

S 32826 Structure

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Quality Control & Documentation
Biological Activity

S 32826 is a inhibitor of autotaxin (IC50 = 9 nM). Displays similar inhibitory effects at all three autotaxin isoforms (α, β and γ). Exhibits no affinity for lysophosphatidic acid receptor 1 (LPA1) at concentrations up to 10 μM. Inhibits LPA release from adipocytes (IC50 = 90 nM).

Chemical Information
Molecular Weight 441.45
Formula C21H34NO4PNa2
CAS Number 1103672-43-0
Solubility (25°C) 1eq. NaOH 44.15 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Koe, et al. J Pharmacol Exp Ther. Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotonin.

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Keywords: S 32826 supplier, inhibitors, activators

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