Free shipping on all orders over $ 500

S 24795

Cat. No. M8445

All AbMole products are for research use only, cannot be used for human consumption.

S 24795 Structure

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.

Quality Control & Documentation
Biological Activity

S 24795 is a selective partial agonist for the α7-subtype of nicotinic acetylcholine receptor (nAChR). S 24795 was shown to be effective at improving learning and memory in various animal models relevant to Alzheimer’s disease and age-related memory loss, and is used in investigating the roles of α7 nAChRs in aging, learning, memory, and cognition.

Chemical Information
Molecular Weight 418.07
Formula C14H13BrNO · I
CAS Number 304679-75-2
Solubility (25°C) Water: 1 mg/mL (warmed)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] No authors listed. J Neurosci. Expression of Concern: Wang et al., "Dissociating β-Amyloid from α7 Nicotinic Acetylcholine Receptor by a Novel Therapeutic Agent, S 24795, Normalizes α7 Nicotinic Acetylcholine and NMDA Receptor Function in Alzheimer's Disease Brain"

[2] Hoau-Yan Wang, et al. S 24795 limits beta-amyloid-alpha7 nicotinic receptor interaction and reduces Alzheimer's disease-like pathologies

[3] Hoau-Yan Wang, et al. Dissociating beta-amyloid from alpha 7 nicotinic acetylcholine receptor by a novel therapeutic agent, S 24795, normalizes alpha 7 nicotinic acetylcholine and NMDA receptor function in Alzheimer's disease brain

[4] Laura Lagostena, et al. The partial alpha7 nicotine acetylcholine receptor agonist S 24795 enhances long-term potentiation at CA3-CA1 synapses in the adult mouse hippocampus

[5] Gretchen Lopez-Hernandez, et al. Partial agonist and neuromodulatory activity of S 24795 for alpha7 nAChR responses of hippocampal interneurons

Related Products
Poly-L-lysine (MW 150000~300000)

Poly-L-lysine
N-Phenylacrylamide

N-Phenylacrylamide
Silver diethyldithiocarbamate

Silver diethyldithiocarbamate is used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues.
Methylmalonic acid

Methylmalonic acid can be used as a substrate in esterification reactions by various catalysts.
Sarcosine

Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
  Catalog
Abmole Inhibitor Catalog




Keywords: S 24795 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.


 
Get to Know Us
Customer Support
Resources
Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.