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Ruscogenin is an important steroid saponin extracted from Ophiopogon japonicum. It alleviates blood-brain barrier dysfunction induced by cerebral ischemia by inhibiting TXNIP/NLRP3 inflammatory body activation and MAPK pathway, and has significant anti-inflammatory and antithrombotic activities. Ruscogenin has orally bioactivity.
| Molecular Weight | 430.62 |
| Formula | C27H42O4 |
| CAS Number | 472-11-7 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Zhiwang Song, et al. Ruscogenin induces ferroptosis in pancreatic cancer cells
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