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RU 28318, potassium salt is a potent and selective antagonist for the mineralocorticoid receptor (MR). Inhibits aldosterone production and secretion, and selectively decreases ex-vivo MR binding in the hippocampus of adrenalectomised rats. Also decreases blood pressure in female rats following central administration in vivo.
| Molecular Weight | 440.66 |
| Formula | C25H37O4K |
| CAS Number | 76676-34-1 |
| Solubility (25°C) | Water 44.07 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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