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RTS-V5

Cat. No. M10883

All AbMole products are for research use only, cannot be used for human consumption.

RTS-V5  Structure

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Quality Control & Documentation
Biological Activity

RTS-V5 is an inhibitor of HDAC/proteasomes, against HDAC1, HDAC2, HDAC3, HDAC6, HDAC8IC50They were 6.9, 18, 15, 0.27, 0.53 μM, respectively.

Chemical Information
Molecular Weight 525.61
Formula C27H35N5O6
CAS Number 2285346-31-6
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kazuki Okubo, et al. Anticancer Res. The Dual Histone Deacetylase-Proteasome Inhibitor RTS-V5 Acts Synergistically With Ritonavir to Induce Endoplasmic Reticulum Stress in Bladder Cancer Cells

[2] Kazuki Okubo, et al. Anticancer Res. Ubiquitin-proteasome System Is a Promising Target for Killing Cisplatin-resistant Bladder Cancer Cells

[3] Sanil Bhatia, et al. J Med Chem. Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor

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  Catalog
Abmole Inhibitor Catalog




Keywords: RTS-V5 supplier, HDAC, inhibitors, activators

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