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RS 25344 hydrochloride is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 values are 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively). Inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro.
| Molecular Weight | 411.8 |
| Formula | C19H13N5O4.HCl |
| CAS Number | 152815-28-6 |
| Solubility (25°C) | Water 20.59 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Good, et al. Biochemistry. Hydrogen ion buffers for biological research.
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