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RR6 is a potent, selective, reversible, competitive and orally active vanin inhibitor with an IC50 of 540 nM for recombinant vanin-1. RR6 also potently inhibits human, bovine and rat serum pantetheinase with IC50 values of 40 nM, 41 nM and 87 nM, respectively.
| Molecular Weight | 293.36 |
| CAS Number | 1351758-37-6 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Hiroki Yoneyama, et al. Design, synthesis, and evaluation of new vanin-1 inhibitors based on RR6
[5] Joost Schalkwijk, et al. Chemical biology tools to study pantetheinases of the vanin family
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