All AbMole products are for research use only, cannot be used for human consumption.
Camonsertib (RP-3500) is an orally potent, selective ATR kinase inhibitor (ATRi) in biochemical assays IC50 1.00 nM. The RP-3500 is 30 times more selective to ATR (IC).50=120 nM), which is 2,000 times > ATM, DNA-PK, and PI3Kα kinase.
| Molecular Weight | 410.47 |
| Formula | C21H26N6O3 |
| CAS Number | 2417489-10-0 |
| Solubility (25°C) | DMSO 45 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
| Related ATM/ATR Products |
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| KU-55933
KU-55933 is a cell-permeable ATP-competitive inhibitor of ATM (IC50 = 13 nM; Ki = 2.2 nM) with selectivity over other PIKK family kinases (IC50 = 2.5, 9.3, 16.6 μM for DNAPK, mTOR, PI 3-K, respectively; IC50 > 100 μM for PI 4-K and ATR). |
| KU-60019
KU-60019 is a potent ATM kinase inhibitor with IC50 of 6.3 nM. |
| VE-821
VE-821 is a highly selective and potent ATR inhibitor with IC50 of 26 nM. |
| ETP-46464
ETP-46464 is a potent inhibitor against mTOR, ATR, DNA-PK, PI 3-Kα and ATM with IC50 of 0.6, 14, 36, 170 and 545 nM, respectively. |
| CP-466722
Cp-466722 is a reversible ATM inhibitor with IC50 value of 4.1 μM, but has no effect on PI3K, PIKK family proteins. |
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Products are for research use only. Not for human use. We do not sell to patients.
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