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Rosiptor (AQX-1125) acetate is a selective and orally active phosphatase SHIP1 activator with anti-inflammatory effects. Rosiptor acetate (AQX-1125) inhibits Akt phosphorylation, inflammatory mediator production and leukocyte chemotaxis in vitro.
| Molecular Weight | 381.55 |
| Formula | C22H39NO4 |
| CAS Number | 782487-29-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] Kenzo Yahata, et al. Org Lett. Second-Generation Total Synthesis of Prorocentin
[4] Michael Ricca, et al. Org Biomol Chem. Chemistry and biology of spiroacetals from myxobacteria
| Related Phosphatase Products |
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CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM. |
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Microcystin-LR is a potent protein phosphatase inhibitor with IC50 of 0.04 nM for PP2A, >40-fold selectivity over PP1. |
| Sal003
Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor. |
| Razuprotafib
Razuprotafib (AKB-9778) is an effective selective inhibitor of VE-PTP (HPTPß) catalytic activity (IC50=17 pM). |
| β-Glycerophosphate disodium salt hydrate
β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. |
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