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Roquefortine C

Cat. No. M39035

All AbMole products are for research use only, cannot be used for human consumption.

Roquefortine C Structure
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1mg USD 550 In stock
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Quality Control & Documentation
Biological Activity

Roquefortine C, a fungal cyclopeptide isolated from Penicillium roquefortii, activates P-gp and also inhibits P450-3A and other haemoproteins. Roquefortine C has bacteriostatic activities against Gram-positive bacteria.

Chemical Information
Molecular Weight 389.45
Formula C22H23N5O2
CAS Number 58735-64-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] C M Maragos. Food Addit Contam Part B Surveill. Roquefortine C in blue-veined and soft-ripened Cheeses in the USA

[2] K Kosalková et al. Appl Microbiol Biotechnol. A natural short pathway synthesizes roquefortine C but not meleagrin in three different Penicillium roqueforti strains

[3] Asheesh K Tiwary et al. J Vet Diagn Invest. Using roquefortine C as a biomarker for penitrem A intoxication

[4] Ning Shangguan et al. J Am Chem Soc. The total synthesis of roquefortine C and a rationale for the thermodynamic stability of isoroquefortine C over roquefortine C

[5] C Finoli et al. J Food Prot. Roquefortine C occurrence in blue cheese

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Keywords: Roquefortine C supplier, P-glycoprotein, inhibitors, activators

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