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Roburic acid is a tetracyclic triterpenoid in Gentiana macrophylla. As an inhibitor of COX, the IC50 values of COX-1 and COX-2 are 5 and 9 μM, respectively.
| Molecular Weight | 440.70 |
| Formula | C30H48O2 |
| CAS Number | 6812-81-3 |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Shu-Bing Hou, et al. Seven new chemical constituents from the roots of Gentiana macrophylla pall
| Related COX Products |
|---|
| Firocoxib
Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2. |
| Celecoxib
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively). |
| Nepafenac
Nepafenac is an analgesic selective inhibitor of COX-2. |
| Ampiroxicam
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound. |
| Bromfenac Sodium
Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. |
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