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Robatumumab

Cat. No. M25294

All AbMole products are for research use only, cannot be used for human consumption.

Robatumumab Structure
Synonym:

Sch 717454; 19D12

Size Price Availability Quantity
100ug USD 160 In stock
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Biological Activity

Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research.

Chemical Information
CAS Number 934235-44-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Hemant K Bid, et al. Mol Cancer Ther. Potent inhibition of angiogenesis by the IGF-1 receptor-targeting antibody SCH717454 is reversed by IGF-2

[2] Giorgio V Scagliotti, et al. Cancer Treat Rev. The role of the insulin-like growth factor signaling pathway in non-small cell lung cancer and other solid tumors

[3] Yaolin Wang, et al. Mol Cancer Ther. A fully human insulin-like growth factor-I receptor antibody SCH 717454 (Robatumumab) has antitumor activity as a single agent and in combination with cytotoxics in pediatric tumor xenografts

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Keywords: Robatumumab, Sch 717454; 19D12 supplier, IGF-1R, inhibitors, activators

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