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Ro 10-5824 dihydrochloride

Cat. No. M7204

All AbMole products are for research use only, cannot be used for human consumption.

Ro 10-5824 dihydrochloride Structure

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Quality Control & Documentation
Biological Activity

Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist (EC50 = 205 nM) that binds with high affinity (Ki = 5.2 nM). Displays 250-fold selectivity over D3 receptors and > 1000-fold selectivity over D2, D1 and D5 receptors.

Chemical Information
Molecular Weight 353.29
Formula C17H20N4.2HCl
CAS Number 189744-94-3
Solubility (25°C) DMSO 26.5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Evans, et al. Br J Pharmacol. Antagonism of excitatory amino acid-induced responses and of synaptic excitation in the isolated spinal cord of the frog.

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