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Rivastigmine (S-Rivastigmine) is an orally active, potent cholinesterase (ChE) inhibitor that inhibits butyrylcholinesterase (BChE) and acetylcholinesterase (AChE),IC50 0.037 μM and 4.15 μM, respectively. Rivastigmine can pass through the blood-brain barrier (BBB). Rivastigmine is an parasympathetic or cholinergic agent used to study dementia caused by mild to moderate Alzheimer's and Parkinson's disease.
| Molecular Weight | 250.34 |
| Formula | C14H22N2O2 |
| CAS Number | 123441-03-2 |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Kevin Nguyen, et al. Neurodegener Dis Manag. Evaluation of rivastigmine in Alzheimer's disease
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